In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Exploring Electrochemical C(sp3)-H Oxidation for the Late-Stage Methylation of Complex Molecules, published in 2022-01-26, which mentions a compound: 110-52-1, Name is 1,4-Dibromobutane, Molecular C4H8Br2, Reference of 1,4-Dibromobutane.
A modular, efficient and selective strategy for the α-methylation of protected amines (i.e., amides, carbamates and sulfonamides) by means of electrochem. oxidation was disclosed. Mechanistic anal. guided to develop an improved electrochem. protocol on the basis of the classic Shono oxidation reaction, which featured broad reaction scope, high functional group compatibility and operational simplicity. Importantly, this reaction system was amenable to the late-stage functionalization of complex targets containing basic nitrogen groups that was prevalent in medicinally active agents. When combined with organozinc-mediated C-C bond formation, this protocol enabled the direct methylation of a myriad of amine derivatives including those that have previously been explored for the “”magic methyl”” effect. This synthetic strategy thus circumvented multistep de novo synthesis that was currently necessary to access such compounds and has the potential to accelerate drug discovery efforts.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles