An article Anti-cancer potential of novel glycosylated 1,4-substituted triazolylchalcone derivatives WOS:000485100200014 published article about BIOLOGICAL-ACTIVITY; CANCER; CHALCONE; 1,2,3-TRIAZOLES; PROTEIN in [Manna, Tapasi; Pal, Kunal; Jana, Kuladip; Misra, Anup Kumar] Bose Inst, Div Mol Med, P-1-12,CIT Scheme 7 M, Kolkata 700054, India in 2019.0, Cited 30.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Computed Properties of C8H8O2
A series of glycosylated 1,4-substituted triazolyl chalcone derivatives (8a-f and 14a-r) were synthesized in high yield using 1,3-cycloaddition (Click chemistry) of D-glucosyl azides with a variety of propargylated chalcone derivatives followed by de-O-acetylation. The synthesized compounds were evaluated for their cytotoxic potential against the human breast carcinoma cell lines and non-cancerous cells. The MTT assay identified three promising cytotoxic compounds (14c, 14i and 14l) and further biochemical and microscopic studies were carried out with the best compound 14i among the active compounds.
About 4′-Hydroxyacetophenone, If you have any questions, you can contact Manna, T; Pal, K; Jana, K; Misra, AK or concate me.. Computed Properties of C8H8O2
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles