An article Direct synthesis of pentasubstituted pyrroles and hexasubstituted pyrrolines from propargyl sulfonylamides and allenamides WOS:000659550700001 published article about INTERMOLECULAR NITRENE TRANSFER; POLYSUBSTITUTED PYRROLES; SUBSTITUTED PYRROLES; REGIOSELECTIVE SYNTHESIS; 3-COMPONENT REACTION; SELECTIVE SYNTHESIS; MULTICOMPONENT; ALKYNES; AMINES; CYCLOADDITION in [Ye, Changqing; Jiao, Yihang; Chiou, Mong-Feng; Li, Yajun; Bao, Hongli] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem Ctr Excellence Mol Synt, Key Lab Coal Ethylene Glycol & Its Related Techno, 155 Yangqiao Rd West, Fuzhou 350002, Fujian, Peoples R China; [Bao, Hongli] Univ Chinese Acad Sci, Beijing 100049, Peoples R China in 2021, Cited 73. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Name: 4-Methoxybenzaldehyde
Multisubstituted pyrroles are important fragments that appear in many bioactive small molecule scaffolds. Efficient synthesis of multisubstituted pyrroles with different substituents from easily accessible starting materials is challenging. Herein, we describe a metal-free method for the preparation of pentasubstituted pyrroles and hexasubstituted pyrrolines with different substituents and a free amino group by a base-promoted cascade addition-cyclization of propargylamides or allenamides with trimethylsilyl cyanide. This method would complement previous methods and support expansion of the toolbox for the synthesis of valuable, but previously inaccessible, highly substituted pyrroles and pyrrolines. Mechanistic studies to elucidate the reaction pathway have been conducted.
Name: 4-Methoxybenzaldehyde. Welcome to talk about 123-11-5, If you have any questions, you can contact Ye, CQ; Jiao, YH; Chiou, MF; Li, YJ; Bao, HL or send Email.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles