An article Stereospecific Electrophilic Fluorocyclization of alpha,beta-Unsaturated Amides with Selectfluor WOS:000526335800030 published article about RADICAL AMINOFLUORINATION; MEDICINAL CHEMISTRY; FLUORINATION; ALKENES; STRATEGIES; HALOFUNCTIONALIZATION; GENERATION; ALKALOIDS; CENTERS; ESTERS in [Xu, Zheyuan; Fu, Yao] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, CAS Key Lab Urban Pollutant Convers, Anhui Prov Key Lab Biomass Clean Energy,iChEM, Hefei 230026, Anhui, Peoples R China; [Fei, Haiyang; Wu, Hongmiao; Zhu, Lin; Lu, Hongjian] Nanjing Univ, Inst Chem & BioMed Sci, Jiangsu Key Lab Adv Organ Mat, Sch Chem & Chem Engn, Nanjing 210093, Peoples R China; [Jalani, Hitesh B.] Yonsei Univ, Dept Pharm, Incheon 21983, South Korea; [Jalani, Hitesh B.] Yonsei Univ, Yonsei Inst Pharmaceut Sci, Incheon 21983, South Korea; [Li, Guigen] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA in 2020, Cited 55. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1. Safety of (E)-2-Methylbut-2-enoic acid
An efficient fluorocyclization of alpha,beta-unsaturated amides through a formal halocyclization process is developed. The reaction proceeds under transition-metal-free conditions and leads to the formation of fluorinated oxazolidine-2,4-diones with excellent regio- and diastereoselectivity. The evaluation of the reaction mechanism based on preliminary experiments and density functional theory calculations suggests that a synergetic syn-oxo-fluorination occurs and is followed by an anti-oxo substitution reaction. The reaction opens a new window in the field of stereospecific fluorofunctionalization.
Safety of (E)-2-Methylbut-2-enoic acid. About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Fei, HY; Xu, ZY; Wu, HM; Zhu, L; Jalani, HB; Li, GG; Fu, Y; Lu, HJ or concate me.
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,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles