Wu, Jiaping; Qian, Baiyang; Lu, Lili; Yang, Haitao; Shang, Yongjia; Zhang, Jitan published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Access to the C2 C-H olefination, alkylation and deuteration of indoles by rhodium(III) catalysis: an opportunity for diverse syntheses》.Recommanded Product: 399-52-0 The article contains the following contents:
A concise approach for the synthesis of structurally diverse indoles enabled by RhIII-catalyzed switchable C2 C-H olefination and alkylation of N-quinolinyl indoles with alkenes as well as highly efficient C-H deuteration was described. The reaction could be conducted under practical reaction conditions, with a broad substrate scope and good tolerance of various functional groups. The potential value of this synthetic methodol. was shown by the diverse late-stage modification of the products, thereby providing a straightforward route to access functionalized indoles, especially indole-based P,N ligands. In addition to this study using 5-Fluoro-1H-indole, there are many other studies that have used 5-Fluoro-1H-indole(cas: 399-52-0Recommanded Product: 399-52-0) was used in this study.
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Fluorine-containing aromatics have been incorporated into crop-protection chemicals (herbicides, insecticides, fungicides). Liquid crystals, positron emission tomography, and imaging systems represent new areas where fluoroaromatics and fluoroheterocyclics have gained attention.Recommanded Product: 399-52-0
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles