Xiao, Jun-An published the artcileGold/scandium bimetallic relay catalysis of formal [5+2]- and [4+2]-annulations: access to tetracyclic indole scaffolds, SDS of cas: 13523-93-8, the main research area is alkynylaryl cyclopropane diester indole gold scandium catalyst regioselective cycloaddition; dimethyl dihydrobenzocycloheptaindolyl methylmalonate preparation; ethynylphenyl cyclopropane dicarboxylate indole gold scandium catalyst regioselective cycloaddition; dimethylbenzocarbazolyl methyl dimethylmalonate preparation.
Regiodivergent formal [5+2]- and [4+2]-annulation reactions of indole derivatives with 2-(2-alkynyl)aryl cyclopropane-1,1-diesters (ACPs) was developed. A series of tetracyclic indole derivatives were delivered in a 77% average yield with excellent regioselectivities enabled by Au(I)/Sc(III) bimetallic relay catalysis. A gram-scale reaction and further transformation of the resulting tetracyclic indoles demonstrated the practical utility of this protocol. Moreover, the photophys. properties of the obtained multicyclic compounds were also investigated.
Chemical Communications (Cambridge, United Kingdom) published new progress about [4+2] Cycloaddition reaction (regioselective). 13523-93-8 belongs to class indole-building-block, name is 4-(Benzyloxy)-1-methyl-1H-indole, and the molecular formula is C16H15NO, SDS of cas: 13523-93-8.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles