MCM-41-accelerated PWA catalysis of Friedel-Crafts reaction of indoles and isatins was written by Xing, Liuzhuang;Hui, YongHai;Yang, Jinghui;Xing, Xuejian;Hou, Yadong;Wu, Yang;Fan, Kui;Wang, Wei. And the article was included in Journal of Chemistry in 2018.COA of Formula: C8H6N2O2 This article mentions the following:
Ordered mesoporous siliceous material has been identified as one of the key elements of the catalysis concept. Herein, an efficient Friedel-Crafts reaction of indoles with isatins catalyzed by PWA/MCM-41, to obtain di(indolyl)indolin-2-one derivatives I (R1 = H, 2-Me, 5-F, etc.; R2 = H, 5-Me, 7-F, etc.) with high yield is reported. Moreover, the catalysts were characterized by XRD and SEM/EDS, the EDS spectrum indicated that the catalyst used in this reaction also contains tungsten, and the proposed mechanism for the synthesis of 3,3-di(indolyl)indolin-2-ones was also discussed. Finally, the catalyst can be reused repeatedly for several times without obvious loss of activity. In the experiment, the researchers used many compounds, for example, 6-Nitro-1H-indole (cas: 4769-96-4COA of Formula: C8H6N2O2).
6-Nitro-1H-indole (cas: 4769-96-4) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.COA of Formula: C8H6N2O2
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles