Previous studies have identified that indole-oxidases are present in P. putida, whose major ligands are heterocyclic substrates and have an interesting affinity when the substrate is indole. 19005-93-7, formula is C9H7NO, Name is 1H-Indole-2-carbaldehyde. These enzymes oxidize the ring so the substrate turns into Indigo. Synthetic Route of 19005-93-7.
Xing, Siyang;Wang, Yuhan;Jin, Changkun;Shi, Shaochen;Zhang, Yihui;Liao, Ziya;Wang, Kui;Zhu, Bolin research published 《 Construction of Bridged Aza- and Oxa-[n.2.1] Skeletons via an Intramolecular Formal [3 + 2] Cycloaddition of Aziridines and Epoxides with Electron-deficient Alkenes》, the research content is summarized as follows. An intramol. formal [3+2] cycloaddition of activated aziridines and epoxides with electron-deficient alkene I (X = N,O; R1 = Me, Et, n-Pr, i-Pr, n-bu, Bn; R3 = H, F, Cl; R4 = H, OMe, CF3; R5 = H, Me; R2 = 4-Br6H4, 4-NO2C6H4, C6H5) has been developed for the general and efficient construction of bridged aza- and oxa-[n.2.1] (n = 3,4) II skeletons. The strategy can be promoted by lithium iodide efficiently. In order to demonstrate its potential, the intramol. formal [3 + 2] cycloaddition was used to access the important intermediate of homoepiboxidine.
19005-93-7, 1H-Indole-2-carbaldehyde is a useful research compound. Its molecular formula is C9H7NO and its molecular weight is 145.16 g/mol. The purity is usually 95%.
1H-Indole-2-carbaldehyde is a useful research chemical used as a reactant in the synthesis of substituted 2-amino-4H-chromenes and benzochromenes using K2CO3 as catalyst.
1H-Indole-2-carbaldehyde is a solvent that has been used in the protein data and molecular modeling study. The 1H NMR spectrum of this compound showed an intense signal at δ 4.8 ppm, corresponding to the hydroxyl proton. This solvent also has fluorescence properties, as shown by its photophysical and structural analysis. The 1H-indole-2-carbaldehyde molecule has an active methylene group and an oxindole ring with amine substituents., Synthetic Route of 19005-93-7
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles