Oxidative coupling of indoles with ethyl 2-(disubstituted amino)acetates: An approach to achieve indolylglycine derivatives was written by Xu, Zhanwei;Yu, Xiaoqiang;Feng, Xiujuan;Bao, Ming. And the article was included in Journal of Organic Chemistry in 2012.Computed Properties of C8H8N2 This article mentions the following:
An efficient method for the synthesis of indolylglycine derivatives is described. The oxidative coupling reactions of Et 2-(disubstituted amino)acetates with indoles proceeded smoothly in the presence of meta-chloroperoxybenzoic acid (mCPBA) under ambient conditions to produce indolylglycine derivatives in satisfactory to excellent yields. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-pyrrolo[2,3-b]pyridine (cas: 27257-15-4Computed Properties of C8H8N2).
1-Methyl-1H-pyrrolo[2,3-b]pyridine (cas: 27257-15-4) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Computed Properties of C8H8N2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles