Synthesis of some symmetric disulfides from thiophthalimides and amines under microwave irradiation was written by Yakan, Hasan;Karakullukcu, Nalan Turkoz;Cakmak, Sukriye;Kutuk, Halil. And the article was included in Research Journal of Chemistry and Environment in 2018.HPLC of Formula: 14204-27-4 This article mentions the following:
Some sym. disulfides were astonishingly prepared from thiophthalimides (sulfenimides) and amines in the presence of 2-ethoxyethanol (尾-ee, neat) at microwave irradiation under free catalyst and ligand. The products were obtained in good to excellent yields ranging from 62% to 92%. When only thiophthalimides were exposed to microwave irradiation, disulfides were not obtained. Also, disulfides were not obtained from thiophthalimides in the presence of 2-ethoxyethanol (neat) under microwave irradiation The microwave-assisted synthesis method was compared with the classical method. The products obtained were purified with chromatog. method and the anal. of them was performed with IR, 1H NMR, 13C NMR spectroscopic and elemental methods. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4HPLC of Formula: 14204-27-4).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.HPLC of Formula: 14204-27-4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles