Yang, Xiao-Hui published the artcileIntermolecular Hydroamination of 1,3-Dienes To Generate Homoallylic Amines, Name: 4-Chloroindoline, the main research area is rhodium catalyzed intermol hydroamination diene Bronsted acid BINAP effect; homoallylic amine preparation anti Markovnikov selectivity.
Authors report a Rh-catalyzed hydroamination of 1,3-dienes to generate homoallylic amines. The work show-cases the first case of anti-Markovnikov selectivity in the intermol. coupling of amines and 1,3-dienes. By tuning the ligand properties and Bronsted acid additive, it was found that a combination of rac-BINAP and mandelic acid is critical for achieving anti-Markovnikov selectivity.
Journal of the American Chemical Society published new progress about Addition reaction (anti-Markovnikov). 41910-64-9 belongs to class indole-building-block, name is 4-Chloroindoline, and the molecular formula is C8H8ClN, Name: 4-Chloroindoline.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles