Gold(I)-catalyzed rearrangement of alkynylaziridine indoles for the synthesis of spiro-tetrahydro-尾-carbolines was written by Yang, Yan-Fang;Li, Lian-Hua;He, Yu-Tao;Luo, Jian-Yi;Liang, Yong-Min. And the article was included in Tetrahedron in 2014.SDS of cas: 111258-23-2 This article mentions the following:
Functionalized spiro-tetrahydro-尾-carbolines were formed by an efficient gold(I)-catalyzed rearrangement reaction of alkynylaziridine indoles. The reaction involved a Friedel-Crafts type intramol. reaction of alkynylaziridine indoles, following by hydroamination of aminoallene intermediate. In the experiment, the researchers used many compounds, for example, Methyl 4-methoxy-1H-indole-2-carboxylate (cas: 111258-23-2SDS of cas: 111258-23-2).
Methyl 4-methoxy-1H-indole-2-carboxylate (cas: 111258-23-2) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.SDS of cas: 111258-23-2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles