Sano, K; Kuribara, T; Ishii, N; Kuroiwa, A; Yoshihara, T; Tobita, S; Totani, K; Matsuo, I in [Sano, Kanae; Ishii, Nozomi; Kuroiwa, Ayumi; Yoshihara, Toshitada; Tobita, Seiji; Matsuo, Ichiro] Gunma Univ, Grad Sch Sci & Technol, 1-5-1 Tenjin Cho, Kiryu, Gunma 3768515, Japan; [Kuribara, Taiki; Totani, Kiichiro] Seikei Univ, Dept Mat & Life Sci, 3-3-1 Kichijoji Kitamachi, Musashino, Tokyo 1808633, Japan published Fluorescence Quenching-based Assay for Measuring Golgi endo-alpha-Mannosidase in 2019.0, Cited 29.0. Formula: C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.
Golgi endo-alpha-mannosidase (G-EM) catalyzes an alternative deglucosylation process for N-glycans and plays important roles in the post-endoplasmic reticulum (ER) quality control pathway. To understand the post-ER quality control mechanism, we synthesized a tetrasaccharide probe for the detection of the hydrolytic activity of G-EM based on a fluorescence quenching assay. The probe was labeled with an N-methylanthraniloyl group as a reporter dye at the non-reducing end and a 2,4-dinitrophenyl group as a quencher at the reducing end. This probe is hydrolyzed to disaccharide derivatives by G-EM, resulting in increased fluorescence intensity. Thus, the fluorescence signal is directly proportional to the amount of disaccharide derivative present, allowing the G-EM activity to be evaluated easily and quantitatively.
Formula: C7H8O. Bye, fridends, I hope you can learn more about C7H8O, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles