Isolation, identification and antimicrobial activity of secondary metabolites from a soil-derived Streptomyces from arid habitats of Qinghai was written by Yu, Zhi-yin;Yu, Ming-ming;Luo, Jian-ying;Su, Can;Xue, Quan-hong;Huang, Sheng-xiong;Sun, Yun;Ma, Ya-tuan. And the article was included in Tianran Chanwu Yanjiu Yu Kaifa in 2015.Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide This article mentions the following:
Five compounds, including N-acetyltyramine(1), N-acetyltryptamine(2), pyrrole-2-carboxamide(3), inthomycin C(4) and inthomycin B(5), were isolated from the fermentation broth of Streptomyces pactum KIB-HL8, and their structures were elucidated by anal. of NMR and MS data. In addition, compound 4 moderately inhibited growth of Staphylococcus aureus. Compounds 1 and 2 showed significant antifungal activity against Botrytis cinerea. Compound 3 displayed inhibitory activity against Alternaria solani. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide).
N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles