《Rose bengal as photocatalyst: visible light-mediated Friedel-Crafts alkylation of indoles with nitroalkenes in water》 was written by Yu, Zong-Yi; Zhao, Jing-Nan; Yang, Fan; Tang, Xiao-Fei; Wu, Yu-Feng; Ma, Cun-Fei; Song, Bo; Yun, Lei; Meng, Qing-Wei. Electric Literature of C8H6FN And the article was included in RSC Advances in 2020. The article conveys some information:
A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles reacted smoothly with nitroalkenes under the irradiation of visible-light and generated corresponding 3-(2-nitroalkyl)indoles I (R1 = H, 5-F, 6-Me, etc.; R2 = C6H5, 4-FC6H4, 2-thienyl, etc.) in moderate to good yields (up to 87%). In the experiment, the researchers used 5-Fluoro-1H-indole(cas: 399-52-0Electric Literature of C8H6FN)
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Fluorine-containing aromatics have been incorporated into crop-protection chemicals (herbicides, insecticides, fungicides). Liquid crystals, positron emission tomography, and imaging systems represent new areas where fluoroaromatics and fluoroheterocyclics have gained attention.Electric Literature of C8H6FN
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles