Zhang, Chunhui published the artcilePalladium-Catalyzed Direct C-H Carbonylation of Free Primary Benzylamines: A Synthesis of Benzolactams, Formula: C8H6ClNO, the main research area is primary benzylamine carbon monoxide carbonylation palladium; benzolactam preparation; palladium carbonylation.
A protocol for palladium-catalyzed C-H carbonylation of readily available free primary benzylamines using NH2 as the chelating group under an atm. pressure of CO has been achieved, providing a general, atom- and step-economic approach to benzolactams, an important structural motif found in many biol. active compounds Application of this new method is also exemplified in the concise syntheses of two bioactive mols, e.g., (R)-PD 172939.
Organic Letters published new progress about Aralkyl amines Role: RCT (Reactant), RACT (Reactant or Reagent) (primary). 74572-29-5 belongs to class indole-building-block, name is 5-Chloroisoindolin-1-one, and the molecular formula is C8H6ClNO, Formula: C8H6ClNO.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles