Zhang, Guangji et al. published their research in ACS Sustainable Chemistry & Engineering in 2020 | CAS: 4769-96-4

6-Nitro-1H-indole (cas: 4769-96-4) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Synthetic Route of C8H6N2O2

Co,N-Codoped Porous Carbon-Supported CoyZnS with Superior Activity for Nitroarene Hydrogenation was written by Zhang, Guangji;Tang, Feiying;Wang, Xiaoying;An, Ping;Wang, Liqiang;Liu, You-Nian. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Synthetic Route of C8H6N2O2 This article mentions the following:

Preparation of chemoselective hydrogenation catalyst containing both CoNx and CoyZnS supported on N-doped porous carbon (CoNx-CoyZnS@NPC-Z) was reported. The CoNx-CoyZnS@NPC-Z catalyst were prepared by pyrolyzing the protein-metal-ion networks, followed by treatment with acid. The CoNx-CoyZnS@NPC-Z-3 catalyst delivered high catalytic activity and selectivity in chemoselective hydrogenation of nitroarenes afforded aryl amines R-NH2 [R = Ph, 4-ClC6H4, 2-naphthyl, etc.] with almost full conversion and >98% selectivity in water/methanol mixture solvents at 90掳C under 5 bar of H2 pressure for 3h of reaction. Also Schiff-base derivatives R1CH=NR2 [R1 = Ph, 4-ClC6H4, 4-MeOC6H4, etc.; R2 = Ph, 2-MeC6H4, 4-ClC6H4, etc.] were prepared via one-pot reductive amination of aryl aldehydes with aromatic nitro compounds using CoNx-CoyZnS@NPC-3 catalyst. Notably, the catalytic hydrogenation could work even under 1 bar of H2 pressure and at room temperature with high conversion and selectivity. Besides, CoNx-CoyZnS@NPC-Z-3 exhibited remarkable tolerance to CO or H2S poisoning and acid erosion. In the experiment, the researchers used many compounds, for example, 6-Nitro-1H-indole (cas: 4769-96-4Synthetic Route of C8H6N2O2).

6-Nitro-1H-indole (cas: 4769-96-4) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Synthetic Route of C8H6N2O2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles