Zhang, Ming-Zhi; Mulholland, Nick; Seville, Anne; Hough, Gemma; Smith, Nicholas; Dong, Hong-Qiang; Zhang, Wei-Hua; Gu, Yu-Cheng published the artcile< First discovery of pimprinine derivatives and analogs as novel potential herbicidal, insecticidal and nematicidal agents>, Application of C10H9NO, the main research area is pimprinine derivative analog preparation herbicidal insecticidal nematicidal.
Pimprinine and streptochlorin are indole natural products produced by many species of organisms, and they are reported to possess a wide range of biol. activities, such as anticancer, antiviral, antifungal activity and so on. In this study, three series of pimprinine derivatives or analogs were efficiently synthesized under the optimized methods. Biol. assays conducted at Syngenta firstly indicated the pimprinine derivatives or analogs possessed potential herbicidal and insecticidal activity, and this is highlighted by several compounds that possessed significant biol. activity as well as broad spectrum. Meanwhile, compounds with benzothiophene-oxazole core showed effective nematicidal activity in primary screening. Compounds 5-(benzofuran-3-yl)oxazole and 5-(benzodioxol-5-yl)oxazole were identified as the most promising lead structures for further study.
Tetrahedron published new progress about Disease, plant. 4771-48-6 belongs to class indole-building-block, and the molecular formula is C10H9NO, Application of C10H9NO.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles