《TMSCl-catalyzed tandem reaction of dihydroisobenzofuran acetals with indoles》 was written by Zhang, Ming; Lu, Sicong; Li, Guofeng; Hong, Liang. Safety of 5-Fluoro-1H-indoleThis research focused ontosylaminomethylidene ethoxydihydroisobenzofuran indole trimethylchlorosilane tandem aza Michael addition rearrangement; indolyl tosyl tetrahydroisoquinolinone preparation regioselective. The article conveys some information:
A TMSCl-catalyzed tandem reaction of dihydroisobenzofuran acetals with indoles was developed, which provided an efficient and straightforward access to various tetrahydroisoquinolones in moderate to excellent yields. This process involved the first addition of the indoles to acetals, followed by skeletal rearrangement. In the experiment, the researchers used many compounds, for example, 5-Fluoro-1H-indole(cas: 399-52-0Safety of 5-Fluoro-1H-indole)
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Depending on which substituents are present, fluoroaromatic intermediates can be converted into fluorinated or fluorine-free commercial end products.Fluorine-containing aromatics have been incorporated into drugs (hypnotics, tranquilizers, antiinflammatory agents, analgesics, antibacterials).Safety of 5-Fluoro-1H-indole
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles