Ligand-Controlled Palladium-Catalyzed Asymmetric [4+3] and [2+3] Annulation Reactions of Spirovinylcyclopropyl Oxindoles with o-Quinone Methides was written by Zhang, Xiyuan;Zhang, Cong;Jiang, Bo;Gao, Yanfeng;Xu, Xiufang;Miao, Zhiwei. And the article was included in Organic Letters in 2022.HPLC of Formula: 100831-25-2 The following contents are mentioned in the article:
Herein, the regiodivergent ligand-controlled palladium-catalyzed asym. cycloaddition reactions between spirovinylcyclopropyl oxindoles and o-quinone methides was reported. Specifically, by using the chiral P,P-ligand Segphos, various spirooxindole-3,4-benzo[b]oxepanes in moderate to good yields with excellent enantioselectivities via [4+3] cycloaddition reactions was obtained. In contrast, reactions involving Trost’s ligand showed different regio- and stereoselectivities, affording bispirooxindole heterocyclic compounds in good yields via [2+3] cycloaddition reactions. This study involved multiple reactions and reactants, such as 7-Bromo-1-methylindolin-2-one (cas: 100831-25-2HPLC of Formula: 100831-25-2).
7-Bromo-1-methylindolin-2-one (cas: 100831-25-2) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). HPLC of Formula: 100831-25-2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles