On September 30, 2007, Zhang, Yingru; Dai, Jun; Wang-Iverson, David B.; Tymiak, Adrienne A. published an article.Name: H-Idc-OH The title of the article was Simulated moving columns technique for enantioselective supercritical fluid Chromatography. And the article contained the following:
This article describes a very useful extension of an unique column switching technique called Simulated Moving Columns (SMC) that was previously reported for chiral HPLC. SMC uses two or three short chiral columns connected in series, and enables the unresolved enantiomers to sep. repeatedly and exclusively through each of the columns until sufficient resolution is attained. The technique is significantly enhanced through the use of supercritical fluid chromatog. (SFC). The supercritical or near critical carbon dioxide (CO2) used in the mobile phase of SFC possesses the properties of a liquid as well as a gas, and usually results in much sharper peaks compared to HPLC. Consequently, by combining SMC with SFC (SMC-SFC), the authors were able to dramatically increase the number of SMC cycles with significantly less band broadening compared to HPLC. For the 1st time, an enantioselective SFC separation was demonstrated by increasing the column from the actual 20 cm length to reach a half meter virtual length with remarkably enhanced efficiency. Off-column band broadening resulting from a two-column SMC system was measured, and its impact on the enantioselectivity of SMC-SFC is much less than in SMC-HPLC. The experimental process involved the reaction of H-Idc-OH(cas: 79815-20-6).Name: H-Idc-OH
The Article related to enantioselective supercritical fluid chromatog simulated moving column, Organic Analytical Chemistry: Separations and other aspects.Name: H-Idc-OH
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles