Zhu, Shuai published the artcileOrganocatalytic atroposelective construction of axially chiral arylquinones, Application In Synthesis of 69622-40-8, the main research area is axially chiral aryl quinone preparation organocatalytic atroposelective.
Herein, the atroposelective construction of axially chiral arylquinones I [R1 = H, CO2Me, CO2Bn, etc.; R2 = H, 7-Br, 6-OMe, etc.; R3 = H, 6-Me, 7-Ph, etc.; R4 = NH2, OH, NHPh, etc.] and II [X = Cl, Br, I; R5 = t-Bu, C(Me)2CH2CH3; R6 = H, 5-Me, 5-OMe, etc.] by a bifunctional chiral phosphoric acid-catalyzed asym. conjugate addition and central-to-axial chirality conversion was presented. With o-naphthoquinone as both the electrophile and the oxidant, three types of arylation counterparts, namely 2-naphthylamines, 2-naphthols and indoles, were utilized to assemble a series of atropisomeric scaffolds in good yields and excellent enantioselectivities. This approach not only expands the axially chiral library but also offered a route to a class of potential, chiral biomimetic catalysts.
Nature Communications published new progress about Aromatic amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 69622-40-8 belongs to class indole-building-block, name is 2-(tert-Butyl)-5-chloro-1H-indole, and the molecular formula is C12H14ClN, Application In Synthesis of 69622-40-8.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles